Physiological Chemistry

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Nicolai Siegel has received a Consolidator Grant. It is already the second ERC grant in his careers. In his research, Nicolai is interested in how variability in pathogen populations contributes to the establishment of lasting infections.The goal of the project is to better understand how pathogens adapt to their environment and potentially develop resistances. This knowledge should help with the development of new intervention strategies and drugs. more

Metabolites mediate essential cellular responses to the environment, ensuring our survival. Changes in metabolic pathways are also key to how tumors evolve and thrive. Our team has a world-leading record in pioneering the discovery of novel interactions between gene regulatory factors and cellular metabolites or their products and to translate these discoveries toward novel therapies. We seek postdocs for two exciting frontline projects.