Publications

Recent

Synthesis and Macrodomain Binding of Gln-carba-ADPr-peptide.
Engelsma SB, Nardozza AP, de Saint Aulaire P, Overkleeft HS, van der Marel GA, Ladurner AG and Filippov DV.
Chembiochem. 2024 Mar 5:e202300865. doi: 10.1002/cbic.202300865.
PubMed

Smoother: on-the-fly processing of interactome data using prefix sums.
Schmidt MR, Barcons-Simon A, Rabuffo C and Siegel TN.
Nucleic Acids Res. 2024 Jan 28:gkae008. doi: 10.1093/nar/gkae008
PubMed

Single-cell metabolic profiling reveals subgroups of primary human hepatocytes with heterogeneous responses to drug challenge.
Sanchez-Quant E, Richter ML, Colomé-Tatché M and Martinez-Jimenez CP.
Genome Biol. 2023 Oct 17;24(1):234. doi: 10.1186/s13059-023-03075-9.
PubMed

Disordered protein regions partner up the cBAF remodeler for a chromatin dance.
Heimhalt M and Ladurner AG.
Mol Cell. 2023 Nov 2;83(21):3763-3765. doi: 10.1016/j.molcel.2023.10.002.
PubMed

The histone chaperone ANP32B regulates chromatin incorporation of the atypical human histone variant macroH2A.
Mandemaker IK, Fessler E, Corujo D, Kotthoff C, Wegerer A, Rouillon C, Buschbeck M, Jae LT, Mattiroli F and Ladurner AG.
Cell Rep. 2023 Oct 18;42(10):113300. doi: 10.1016/j.celrep.2023.113300.
PubMed

CSF3R T618I Collaborates With RUNX1-RUNX1T1 to Expand Hematopoietic Progenitors and Sensitizes to GLI Inhibition.
Swoboda AS, Arfelli VC, Danese A, Windisch R, Kerbs P, Redondo Monte E, Bagnoli JW, Chen-Wichmann L, Caroleo A, Cusan M, Krebs S, Blum H, Sterr M, Enard W, Herold T, Colomé-Tatché M, Wichmann C and Greif PA.
Hemasphere 2023 Oct 11;7(10):e958. doi: 10.1097/HS9.0000000000000958. eCollection 2023 Oct.
PubMed

epiAneufinder identifies copy number alterations from single-cell ATAC-seq data.
Ramakrishnan A, Symeonidi A, Hanel P, Schmid KT, Richter ML, Schubert M and Colomé-Tatché M.
Nat Commun. 2023 Sept 14:5846. doi.org/10.1038/s41467-023-41076-1.
Article

Pioneers conquer core histones at the chromatin frontier.
Murawska M, Ladurner AG and Margulies CE.
Nat Struct Mol Biol 2023 Aug;30(8):1050-1053. doi: 10.1038/s41594-023-01058-9.
PubMed

Decoding the impact of nuclear organization on antigenic variation in parasites.
Barcons-Simon A, Carrington M and Siegel TN.
Nat Microbiol. 2023 Aug;8(8):1408-1418
PubMed

CIARA: a cluster-independent algorithm for the identification of markers of rare cell types from single-cell sequencing data.
Lubatti G, Stock M, Iturbide A, Ruiz Tejada Segura ML, Riepl M, Tyser RCV, Danese A, Colomé-Tatché M, Theis FJ, Srinivas S, Torres-Padilla M-E and A. Scialdone.
Development 150 (11): dev201264 (2023).
PubMed

The inner nuclear membrane Lem2 coordinates RNA degradation at the nuclear periphery.
Martín Caballero L, Capella M, Barrales RR, Dobrev N, van Emden T, Hirano Y, Suma Sreechakram VN, Fischer-Burkart S, Kinugasa Y, Nevers A, Rougemaille M, Sinning I, Fischer T, Hiraoka Y, and Braun S.
Nature Struct & Mol Biol 2022 29(9):910-921. doi: 10.1038/s41594-022-00831-6.
Article

XPC-PARP complexes engage the chromatin remodeler ALC1 to catalyze global genome DNA damage repair.
Blessing C, Apelt K, van den Heuvel D, Gonzalez-Leal C, Rother MB, van der Woude M, González-Prieto R, Yifrach A, Parnas A, Shah RG, Kuo TT, Boer DEC, Cai J, Kragten A, Kim HS, Schärer OD, Vertegaal ACO, Shah GM, Adar S, Lans H, van Attikum H, Ladurner AG and Luijsterburg MS.
Nat Commun. 2022 Aug 13;13(1):4762. doi: 10.1038/s41467-022-31820-4.
PubMed