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Recent Publications

01.04.2025

  1. Genomic determinants of antigen expression hierarchy in African trypanosomes.
    Keneskhanova Z, McWilliam KR, Cosentino RO, Barcons-Simon A, Dobrynin A, Smith JE, Subota I, Mugnier MR, Colomé-Tatché M, Siegel TN.
    Nature. 2025 Mar 12.doi: 10.1038/s41586-025-08720-w.

    LMU Press Release
    PubMed

  2. Inter-chromosomal transcription hubs shape the 3D genome architecture of African trypanosomes.
    Rabuffo C, Schmidt MR, Yadav P, Tong P, Carloni R, Barcons-Simon A, Cosentino RO, Krebs S, Matthews KR, Allshire RC and Siegel TN.
    Nat Commun. 2024 Dec 23;15(1) doi: 10.1038/s41467-024-55285-9.
    PubMed
  3. SLAM-seq reveals independent contributions of RNA processing and stability to gene expression in African trypanosomes.
    Luzak V, Osses E, Danese A, Odendaal C, Cosentino RO, Stricker SH, Haanstra JR, Erhard F and Siegel TN.
    Nucleic Acids Res. 2024 Dec 14. doi: 10.1093/nar/gkae1203. Online ahead of print.
    PubMed
  4. Tissue spaces are reservoirs of antigenic diversity for Trypanosoma brucei.
    Beaver AK, Keneskhanova Z, Cosentino RO, Weiss BL, Awuoche EO, Smallenberger GM, Buenconsejo GY, Crilly NP, Smith JE, Hakim JMC, Zhang B, Bobb B, Rijo-Ferreira F, Figueiredo LM, Aksoy S, Siegel TN and Mugnier MR.
    Nature. 2024 Oct 30. doi: 10.1038/s41586-024-08151-z
    PubMed
  5. Synthesis and Macrodomain Binding of Gln-carba-ADPr-peptide.
    Engelsma SB, Nardozza AP, de Saint Aulaire P, Overkleeft HS, van der Marel GA, Ladurner AG and Filippov DV.
    Chembiochem. 2024 Mar 5:e202300865. doi: 10.1002/cbic.202300865.
    PubMed
  6. Smoother: on-the-fly processing of interactome data using prefix sums.
    Schmidt MR, Barcons-Simon A, Rabuffo C and Siegel TN.
    Nucleic Acids Res. 2024 Jan 28:gkae008. doi: 10.1093/nar/gkae008
    PubMed