Recent Publications
14.07.2025
- The Mia40 substrate Mix17 exposes its N-terminus to the cytosolic side of the mitochondrial outer membraneGenomic determinants of antigen expression hierarchy in African trypanosomes.
Resch M, Frickel JS, Dischinger K, Choo RSW, Hell K and Harner ME.
J Cell Sci. 2025 May 1;138(9):jcs263661.
PubMed - Keneskhanova Z, McWilliam KR, Cosentino RO, Barcons-Simon A, Dobrynin A, Smith JE, Subota I, Mugnier MR, Colomé-Tatché M, Siegel TN.
Nature. 2025 Mar 12.doi: 10.1038/s41586-025-08720-w.
LMU Press Release
PubMed - Dbi1 is an oxidoreductase and an assembly chaperone for mitochondrial inner membrane proteins.
Badrie S., Hell K. and Mokranjac D.
EMBO Rep. 2025 Feb;26(4):911-928.
PubMed - Inter-chromosomal transcription hubs shape the 3D genome architecture of African trypanosomes.
Rabuffo C, Schmidt MR, Yadav P, Tong P, Carloni R, Barcons-Simon A, Cosentino RO, Krebs S, Matthews KR, Allshire RC and Siegel TN.
Nat Commun. 2024 Dec 23;15(1) doi: 10.1038/s41467-024-55285-9.
PubMed - SLAM-seq reveals independent contributions of RNA processing and stability to gene expression in African trypanosomes.
Luzak V, Osses E, Danese A, Odendaal C, Cosentino RO, Stricker SH, Haanstra JR, Erhard F and Siegel TN.
Nucleic Acids Res. 2024 Dec 14. doi: 10.1093/nar/gkae1203. Online ahead of print.
PubMed - Tissue spaces are reservoirs of antigenic diversity for Trypanosoma brucei.
Beaver AK, Keneskhanova Z, Cosentino RO, Weiss BL, Awuoche EO, Smallenberger GM, Buenconsejo GY, Crilly NP, Smith JE, Hakim JMC, Zhang B, Bobb B, Rijo-Ferreira F, Figueiredo LM, Aksoy S, Siegel TN and Mugnier MR.
Nature. 2024 Oct 30. doi: 10.1038/s41586-024-08151-z
PubMed - Synthesis and Macrodomain Binding of Gln-carba-ADPr-peptide.
Engelsma SB, Nardozza AP, de Saint Aulaire P, Overkleeft HS, van der Marel GA, Ladurner AG and Filippov DV.
Chembiochem. 2024 Mar 5:e202300865. doi: 10.1002/cbic.202300865.
PubMed - Smoother: on-the-fly processing of interactome data using prefix sums.
Schmidt MR, Barcons-Simon A, Rabuffo C and Siegel TN.
Nucleic Acids Res. 2024 Jan 28:gkae008. doi: 10.1093/nar/gkae008
PubMed