Physiological Chemistry

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2007 - 2003

  • Functional characterization of Mia40p, the central component of the disulfide relay system of the mitochondrial intermembrane space. Grumbt B, Stroobant V, Terziyska N, Israel L, Hell K. J Biol Chem. 2007 Dec 28;282(52):37461-70.
  • Modular paths to 'decoding' and 'wiping' histone lysine methylation. Kustatscher G, Ladurner AG. Curr Opin Chem Biol. 2007 Dec;11(6):628-35.
  • RNA Pol IV plays catch with Argonaute 4. Till S, Ladurner AG. Cell. 2007 Nov 16 ; 131 (4):643-5.
  • An acetylation switch in p53 mediates holo-TFIID recruitment. Li AG, Piluso LG, Cai X, Gadd BJ, Ladurner AG, Liu X. Mol Cell. 2007 Nov 9;28(3):408-21.
  • The disulfide relay system of mitochondria is connected to the respiratory chain. Bihlmaier K, Mesecke N, Terziyska N, Bien M, Hell K, Herrmann JM. J Cell Biol. 2007 Nov 5;179(3):389-95.
  • A conserved motif in Argonaute-interacting proteins mediates functional interactions through the Argonaute PIWI domain. Till S, Lejeune E, Thermann R, Bortfeld M, Hothorn M, Enderle D, Heinrich C, Hentze MW, Ladurner AG. Nat Struct Mol Biol. 2007 Oct;14(10):897-903.
  • Co-localization of CENP-C and CENP-H to discontinuous domains of CENP-A chromatin at human neocentromeres. Alonso A, Fritz B, Hasson D, Abrusan G, Cheung F, Yoda K, Radlwimmer B, Ladurner AG, Warburton PE. Genome Biol. 2007;8 (7):R148.
  • The chromatin-remodeling factor FACT contributes to centromeric heterochromatin independently of RNAi. Lejeune E, Bortfeld M, White SA, Pidoux AL, Ekwall K, Allshire RC, Ladurner AG. Curr Biol. 2007 Jul 17;17(14):1219-24.
  • Association of the Tim14.Tim16 subcomplex with the TIM23 translocase is crucial for function of the mitochondrial protein import motor. Mokranjac D, Berg A, Adam A, Neupert W, Hell K. J Biol Chem. 2007 Jun 22;282(25):18037-45.
  • The sulfhydryl oxidase Erv1 is a substrate of the Mia40-dependent protein translocation pathway. Terziyska N, Grumbt B, Bien M, Neupert W, Herrmann JM, Hell K. FEBS Lett. 2007 Mar 20;581(6):1098-102.
  • Protein import into isolated mitochondria. Mokranjac D, Neupert W. Methods Mol Biol. 2007;372:277-86.
  • Characterization of the preprotein and amino acid transporter gene family in Arabidopsis. Murcha MW, Elhafez D, Lister R, Tonti-Filippini J, Baumgartner M, Philippar K, Carrie C, Mokranjac D, Soll J, Whelan J. Plant Physiol. 2007 Jan ; 143 (1):199-212.
  • Rheostat control of gene expression by metabolites. Ladurner AG. Mol Cell. 2006 Oct 6;24(1):1-11.
  • Structure and function of Tim14 and Tim16, the J and J-like components of the mitochondrial protein import motor. Mokranjac D, Bourenkov G, Hell K, Neupert W, Groll M. EMBO J. 2006 Oct 4;25(19):4675-85.
  • The Nfs1 interacting protein Isd11 has an essential role in Fe/S cluster biogenesis in mitochondria. Adam AC, Bornhövd C, Prokisch H, Neupert W, Hell K. EMBO J. 2006 Jan 11;25(1):174-83.
  • Influence of substrate binding on the mechanical stability of mouse dihydrofolate reductase. Junker JP, Hell K, Schlierf M, Neupert W, Rief M. Biophys J. 2005 Nov; 89 (5):L46-8.Protein import into mitochondria. Mokranjac D, Neupert W. Biochem Soc Trans. 2005 Nov;33(Pt 5):1019-23.
  • Functional and mutational characterization of human MIA40 acting during import into the mitochondrial intermembrane space. Hofmann S, Rothbauer U, Mühlenbein N, Baiker K, Hell K, Bauer MF. J Mol Biol. 2005 Oct 28;353(3):517-28.
  • Deconstructing memory in Drosophila. Margulies C, Tully T, Dubnau J. Curr Biol. 2005 Sep 6;15(17):R700-13.
  • The import motor of the yeast mitochondrial TIM23 preprotein translocase contains two different J proteins, Tim14 and Mdj2. Mokranjac D, Sichting M, Popov-Celeketić D, Berg A, Hell K, Neupert W. J Biol Chem. 2005 Sep 9;280(36): 31608-14.
  • Splicing regulates NAD metabolite binding to histone macroH2A. Kustatscher G, Hothorn M, Pugieux C, Scheffzek K, Ladurner AG. Nat Struct Mol Biol. 2005 Jul;12 (7): 624-5.
  • A disulfide relay system in the intermembrane space of mitochondria that mediates protein import. Mesecke N, Terziyska N, Kozany C, Baumann F, Neupert W, Hell K, Herrmann JM. Cell. 2005 Jul 1;121(7):1059-69.
  • Role of Tim21 in mitochondrial translocation contact sites. Mokranjac D, Popov-Celeketić D, Hell K, Neupert W. J Biol Chem. 2005 Jun 24;280(25):23437-40.
  • The macro domain is an ADP-ribose binding module. Karras GI, Kustatscher G, Buhecha HR, Allen MD, Pugieux C, Sait F, Bycroft M, Ladurner AG. EMBO J. 2005 Jun 1;24(11):1911-20.
  • Hitting transcription in all the right places. Lejeune E, Ladurner AG. Nat Struct Mol Biol. 2005 May;12(5):390-2.
  • Chopped, trapped or tacked--protein translocation into the IMS of mitochondria. Herrmann JM, Hell K. Trends Biochem Sci. 2005 Apr;30(4):205-11.
  • Maintenance of structure and function of mitochondrial Hsp70 chaperones requires the chaperone Hep1. Sichting M, Mokranjac D, Azem A, Neupert W, Hell K. EMBO J. 2005 Mar 9;24(5):1046-56.
  • Mia40, a novel factor for protein import into the intermembrane space of mitochondria is able to bind metal ions. Terziyska N, Lutz T, Kozany C, Mokranjac D, Mesecke N, Neupert W, Herrmann JM, Hell K. FEBS Lett. 2005 Jan 3;579(1):179-84.
  • Tob38, a novel essential component in the biogenesis of beta-barrel proteins of mitochondria. Waizenegger T, Habib SJ, Lech M, Mokranjac D, Paschen SA, Hell K, Neupert W, Rapaport D. EMBO Rep. 2004 Jul;5(7):704-9.
  • Alternative topogenesis of Mgm1 and mitochondrial morphology depend on ATP and a functional import motor. Herlan M, Bornhövd C, Hell K, Neupert W, Reichert AS. J Cell Biol. 2004 Apr 26;165(2):167-73.
  • The J domain-related cochaperone Tim16 is a constituent of the mitochondrial TIM23 preprotein translocase. Kozany C, Mokranjac D, Sichting M, Neupert W, Hell K. Nat Struct Mol Biol. 2004 Mar;11(3):234-41.