Physiological Chemistry
print
Search
Hinweise zur Datenübertragung bei der Google™ Suche
Links and Functions
Breadcrumb Navigation
Content

2017 - 2015

  1. A Poly-ADP-Ribose trigger releases the auto-inhibition of a chromatin remodeling oncogene.
    Singh HR, Nardozza AP, Möller IR, Knobloch G, Kistemaker HAV, Hassler M, Harrer N, Blessing C, Eustermann S, Kotthoff C, Huet S, Mueller-Planitz F, Filippov DV, Timinszky G, Rand KD and Ladurner AG.
    Mol Cell 2017; 68 (5), 860–871.
    PubMed
  2. The fission yeast nucleoporin Alm1 is required for proteasomal degradation of kinetochore components.
    Salas-Pino S, Gallardo P, Barrales RR, Braun S and Daga RR.
    J Cell Biol. 2017; 216(11), 3591-3608.
    PubMed
  3. MacroH2A1.1 regulates mitochondrial respiration by limiting nuclear NAD+ consumption.
    Marjanović MP, Hurtado-Bagès S, Lassi M, Valero V, Malinverni R, Delage H, Navarro M, Corujo D, Guberovic I, Douet J, Gama-Perez P, Garcia-Roves PM, Ahel I, Ladurner AG, Yanes O, Bouvet P, Suelves M, Teperino R, Pospisilik JA, Buschbeck M.
    Nat Struct Mol Biol. 2017; doi: 10.1038/nsmb.3481. [Epub ahead of print]
    PubMed
  4. Cardiolipin mediates membrane and channel interactions of the mitochondrial TIM23 protein import complex receptor Tim50.
    Malhotra K, Modak A, Nangia S, Daman TH, Gunsel U, Robinson VL, Mokranjac D, May ER and Alder NN.
    Sci Adv. 2017; 3(9):e1700532.
    PubMed
  5. Systematic Identification of MCU Modulators by Orthogonal Interspecies Chemical Screening.
    Arduino DM, Wettmarshausen J, Vais H, Navas-Navarro P, Cheng Y, Leimpek A, Ma Z, Delrio-Lorenzo A, Giordano A, Garcia-Perez C, Médard G, Kuster B, García-Sancho J, Mokranjac D, Foskett JK, Alonso MT and Perocchi F.
    Mol Cell. 2017; 67(4):711-723.
    PubMed
  6. The Histone Acetyltransferase Mst2 Protects Active Chromatin from Epigenetic Silencing by Acetylating the Ubiquitin Ligase Brl1.
    Flury V, Georgescu PR, Iesmantavicius V, Shimada Y, Kuzdere T, Braun S and Bühler M.
    Mol Cell. 2017; 67, 1–14.
    PubMed
  7. Remodelers tap into nucleosome plasticity.
    Singh HR, Murawska M and Ladurner AG.
    Nature Structural & Molecular Biology 2017; 24(4): 341-343.
    PubMed
  8. Chemical Crosslinking in Intact Mitochondria.
    Banerjee R, Günsel U and Mokranjac D.
    Methods Mol Biol. 2017; 1567:139-154.
    PubMed
  9. Role of Nhp6 and Hmo1 in SWI/SNF occupancy and nucleosome landscape at gene regulatory regions.
    Hepp MI, Smolle M, Gidi C, Amigo R, Valenzuela N, Arriagada A, Maureira A, Gogol MM, Torrejón M, Workman JL, and Gutiérrez JL.
    Biochim Biophys Acta. 2017; Mar;1860(3):316-326.
    PubMed
  10. Reversing ADP-ribosylation.
    Moeller GK and Timinszky G.
    Elife. 2017; 6. pii: e29942. doi: 10.7554/eLife.29942.
    PubMed

  11. Poly(ADP-Ribose)-Dependent Chromatin Remodeling in DNA Repair.
    Lebeaupin T, Smith R, Huet S and Timinszky G.
    Methods Mol Biol. 2017; 1608; 165-183.
    PubMed
  12. Role of Tim17 in coupling the import motor to the translocation channel of the mitochondrial presequence translocase.
    Demishtein-Zohary K, Günsel U, Marom M, Banerjee R, Neupert W, Azem A and Mokranjac D.
    Elife. 2017 Feb 6;6. pii:e22696. doi: 10.7554/eLife.22696
    PubMed
  13. sNASP and ASF1A function through both competitive and compatible modes of histone binding.
    Bowman A, Koide A, Goodman JS, Colling ME, Zinne D, Koide S and Ladurner AG.
    Nucleic Acids Res. 2017 Jan 25;45(2):643-656
    PubMed
  14. ATM induces MacroD2 nuclear export upon DNA damage.
    Golia B, Moeller GK, Jankevicius G, Schmidt A, Hegele A, Preißer J, Tran ML, Imhof A, Timinszky G.
    Nucleic Acids Res. 2017 Jan 9;45(1):244-254
    PubMed
  15. The poly(ADP-ribose)-dependent chromatin remodeler Alc1 induces local chromatin relaxation upon DNA damage.
    Sellou H, Lebeaupin T, Chapuis C, Smith R, Hegele A, Singh HR, Kozlowski M, Bultmann S, Ladurner AG, Timinszky G and Huet S.
    Mol Biol Cell. 2016 Dec 1;27(24):3791-3799
    PubMed
  16. Nick Your DNA, Mark Your Chromatin.
    Nardozza AP and Ladurner AG.
    Mol Cell. 2016 Oct 6;64(1): 7-9.
    PubMed
  17. CENPs and Sweet Nucleosomes Face the FACT.
    Murawska M, Ladurner AG.
    Trends Biochem Sci. 2016 Aug 4. pii: S0968-0004(16)30097-4. doi: 10.1016/j.tibs.2016.07.010.
    PubMed
  18. Synthesis and Macrodomain Binding of Mono-ADP-Ribosylated Peptides.
    Kistemaker HA, Nardozza AP, Overkleeft HS, van der Marel GA, Ladurner AG, Filippov DV.
    Angew Chem Int Ed Engl. 2016 Aug 26;55(36):10634-10638.
    PubMed
  19. Mitochondrial protein import: An unexpected disulfide bond.
    Mokranjac D.
    Cell Biol. 2016 Aug 15;214(4):363-5.
    PubMed
  20. The Metabolic Impact on Histone Acetylation and Transcription in Ageing.
    Peleg S, Feller C, Ladurner AG, Imhof A.
    Trends Biochem Sci. 2016 Aug;41(8):700-11.
    PubMed
  21. Sensitive and Quantitative Three-Color Protein Imaging in Fission Yeast Using Spectrally Diverse, Recoded Fluorescent Proteins with Experimentally-Characterized In Vivo Maturation Kinetics.
    Al-Sady B, Greenstein RA, El-Samad HJ, Braun S, Madhani HD.
    PLoS One. 2016 Aug 1;11(8):e0159292.
    PubMed
  22. The Histone Variant MacroH2A1.2 Is Necessary for the Activation of Muscle Enhancers and Recruitment of the Transcription Factor Pbx1.
    Dell'Orso S, Wang AH, Shih HY, Saso K, Berghella L, Gutierrez-Cruz G, Ladurner AG, O'Shea JJ, Sartorelli V, Zare H.
    Cell Rep. 2016 Feb 9;14(5):1156-68.
    PubMed
  23. Life span extension by targeting a link between metabolism and histone acetylation in Drosophila.
    Peleg S, Feller C, Forne I, Schiller E, Sévin DC, Schauer T, Regnard C, Straub T, Prestel M, Klima C, Schmitt Nogueira M, Becker L, Klopstock T, Sauer U, Becker PB, Imhof A, and Ladurner AG.
    EMBO reports 2016 DOI 10.15252/embr.201541132. Published online 18.01.2016
    Article
  24. Control of heterochromatin localization and silencing by the nuclear membrane protein Lem2.
    Barrales RR, Forn M, Georgescu PR, Sarkadi Z, and Braun S.
    Genes Dev. 2016 Jan 7. [Epub ahead of print]
    PubMed
  25. Protein translocation channel of mitochondrial inner membrane and matrix-exposed import motor communicate via two-domain coupling protein.
    Banerjee R, Gladkova C, Mapa K, Witte G, and Mokranjac D.
    Elife. 2015 Dec 29;4. pii: e11897. doi: 10.7554/eLife.11897.
    PubMed
  26. The histone chaperone sNASP binds a conserved peptide motif within the globular core of histone H3 through its TPR repeats.
    Bowman A, Lercher L, Singh HR, Zinne D, Timinszky G, Carlomagno T, and Ladurner AG.
    Nucleic Acids Res. 2015 Dec 15. pii: gkv1372. [Epub ahead of print]
    PubMed
  27. Cell biology: Architecture of a protein entry gate
    Mokranjac D and Neupert W.
    Nature. 2015 Dec 10;528(7581):201-2.
    PubMed
  28. ATM, MacroH2A.1, and SASP: The Checks and Balances of Cellular Senescence.
    Kozlowski M, Ladurner AG.
    Mol Cell. 2015 Sep 3;59(5):713-5.
    PubMed
  29. Nucleotides regulate the mechanical hierarchy between subdomains of the nucleotide binding domain of the Hsp70 chaperone DnaK.
    Bauer D, Merz DR, Pelz B, Theisen KE, Yacyshyn G, Mokranjac D, Dima RI, Rief M, and Žoldák G.
    Proc Natl Acad Sci U S A. 2015 Aug 18;112(33):10389-94.
    PubMed
  30. Designing Cell-Type-Specific Genome-wide Experiments.
    Handley A, Schauer T, Ladurner AG, and Margulies CE.
    Mol Cell. 2015 May 21;58(4): 621-631.
    PubMed
  31. Genome-Wide Association Analyses Point to Candidate Genes for Electric Shock Avoidance in Drosophila melanogaster.
    Appel M, Scholz CJ, Müller T, Dittrich M, König C, Bockstaller M, Oguz T, Khalili A, Antwi-Adjei E, Schauer T, Margulies C, Tanimoto H, Yarali A.
    PLoS One. 2015 May 18;10(5):e0126986.
    PubMed
  32. Global regulation of heterochromatin spreading by Leo1.
    Verrier L, Taglini F, Barrales RR, Webb S, Urano T, Braun S, and Bayne EH.
    Open Biol. 2015 May;5(5): pii: 150045. doi: 10.1098/rsob.150045.
    PubMed
  33. GxxxG Motifs hold the TIM23 Complex Together.
    Demishtein-Zohary K, Marom M, Neupert W, Mokranjac D, Azem A.
    FEBS J. 2015 Mar 12. doi: 10.1111/febs.13266.
    PubMed
  34. Editorial Overview: Elucidation of Protein Translocation Pathways, Part II.
    Mokranjac D, High S
    J Mol Biol. 2015 Mar 27;427(6 Pt A): 1133-4.
    PubMed
  35. Poly-ADP-ribosylation signaling during DNA damage repair.
    Golia B, Singh HR, and Timinszky G.
    Front Biosci (Landmark Ed) 2015, Jan 1;20: 440-57.
    PubMed
  36. Functional Complementation Analyses Reveal that the Single PRAT-Family Protein of Trypanosoma brucei is a Divergent Homolog of Tim17 in Saccharomyces cerevisiae.
    Weems E, Singha UK, Hamilton V, Smith JT, Waegemann K, Mokranjac D, Chaudhuri M.
    Eukaryot Cell. 2015 Jan 9. pii: EC.00203-14.
    PubMed